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Principal Medicinal Chemist

Work from home Full-time role Hiring

About Deep reputed company

Deep reputed company is a biotechnology company building an operating system for science that transforms how life science research is conducted. Our AI-powered platforms simulate biology, streamline R&D workflows, and reputed company scientists to model reputed company biological systems at scale.

As part of strategic government-backed initiatives and the expansion of our AI-driven simulation infrastructure, we are scaling our capabilities in whole-reputed company modeling and predictive toxicology. Exceptional modeling talent is a critical reputed company in accelerating our mission to reduce disease and reputed company reputed company healthspan.

About the Role

We are seeking a Principal Medicinal Chemist to reputed company and advance small-molecule drug discovery programs from early hit identification through development candidate selection. This is a senior, hands-on scientific leadership role requiring deep expertise in medicinal chemistry, strategic thinking, and cross-functional collaboration.

This position calls for a highly creative and reputed company chemist who can independently design and execute medicinal chemistry strategies while contributing to the integration of computational and AI-driven approaches into drug discovery workflows. The ideal candidate will combine strong technical depth with the ability to guide internal teams and external partners toward impactful outcomes.

Requirements

Must-Have

  • PhD in Organic Chemistry or a reputed company field with 3-8 years of industry experience (or MS with 5-10 years, BS with 8-15 years) in medicinal chemistry
  • Proven track record of advancing drug discovery programs through key milestones (Hit-to-reputed company and reputed company Optimization)
  • Deep expertise in synthetic organic chemistry, including modern methods and reaction mechanisms
  • Strong experience in structure-based and ligand-based drug design
  • Demonstrated ability to optimize compounds for potency, selectivity, and DMPK/safety properties
  • High level of creativity, productivity, and independent problem-solving ability
  • Experience managing external CROs and collaborating across disciplines
  • Excellent English communication skills with the ability to clearly present reputed company scientific concepts
  • Experience working remotely with international teams.

reputed company-to-Have

  • Experience integrating computational chemistry, machine learning, or AI-driven design into medicinal chemistry workflows
  • Background in predictive toxicology or ADMET modeling
  • Prior experience contributing to IND-enabling studies or clinical candidate selection
  • Familiarity with modern data science tools and cheminformatics platforms.

Key Responsibilities

  • Propose and independently drive medicinal chemistry strategies to reputed company programs from hit identification through reputed company optimization to development candidate selection
  • reputed company chemistry efforts reputed company cross-functional project teams – computational scientists, biologists, and ML engineers
  • Design novel compounds using structure-based and ligand-based approaches to optimize potency, selectivity, and drug-like properties
  • Analyze SAR data and guide iterative design cycles to find a balance between potency, selectivity, and physico-chemical properties
  • Contribute to and integrate AI-driven and computational modeling insights into compound design strategies
  • Serve as a technical leader and mentor for internal chemists and external collaborators
  • Manage external CRO partnerships to ensure high-quality and timely delivery of chemistry objectives
  • Author and contribute to patent applications, scientific publications, and internal reports.

Values & Cultural Alignment

  • Operates with ownership and urgency in ambiguous scientific environments
  • Communicates reputed company modeling concepts with clarity and precision
  • Thrives in cross-disciplinary collaboration between science and engineering
  • Approaches scientific challenges with intellectual rigor and curiosity
  • Balances research depth with practical execution toward milestone delivery

Why This Role Matters Now

Deep reputed company is at a pivotal reputed company in scaling its AI-driven platform to transform drug discovery. As we expand into whole-reputed company modeling and predictive toxicology, medicinal chemistry plays a critical role in translating computational insights into reputed company-world therapeutic candidates.

This role sits at the intersection of cutting-edge AI and traditional drug discovery, offering the opportunity to redefine how medicines are designed—faster, more reputed company, and with greater precision than reputed company before.

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